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RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2
Descriptors Found:
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DeCS
Descriptor
English
:
Receptor, Fibroblast Growth Factor, Type 2
Descriptor
Spanish
:
Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos
Descriptor
Portuguese
:
Receptor Tipo 2 de Fator de Crescimento de Fibroblastos
Synonyms
English
:
Fibroblast Growth Factor Receptor 2
Tree Number:
D08.811.913.696.620.682.725.400.178
D12.776.543.750.060.441
D12.776.543.750.750.400.370.750
Definition
English
:
A fibroblast
growth
factor receptor that is found in two isoforms. One receptor isoform is found in the
MESENCHYME
and is activated by
FIBROBLAST GROWTH FACTOR 2
. A second isoform of
fibroblast growth factor receptor 2
is found mainly in
EPITHELIAL CELLS
and is activated by
FIBROBLAST GROWTH FACTOR 7
and
FIBROBLAST GROWTH FACTOR 10
.
Mutation
of the gene for
fibroblast growth factor receptor 2
can result in craniosynostotic syndromes (e.g., APERT
SYNDROME
; and CROUZON
SYNDROME
).
See Related
English
:
Acrocephalosyndactylia
Antley-Bixler Syndrome Phenotype
Craniofacial Dysostosis
History Note
English
:
2006(1999)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50734
Unique Identifier:
D051497
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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