Search on: RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2 
Descriptors Found: 1
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Descriptor English:   Receptor, Fibroblast Growth Factor, Type 2 
Descriptor Spanish:   Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos 
Descriptor Portuguese:   Receptor Tipo 2 de Fator de Crescimento de Fibroblastos 
Synonyms English:   Fibroblast Growth Factor Receptor 2  
Tree Number:   D08.811.913.696.620.682.725.400.178
D12.776.543.750.060.441
D12.776.543.750.750.400.370.750
Definition English:   A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME). 
See Related English:   Acrocephalosyndactylia
Antley-Bixler Syndrome Phenotype
Craniofacial Dysostosis
 
History Note English:   2006(1999) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50734 
Unique Identifier:   D051497 

Occurrence in VHL:
 

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